Agaricus subrufescens (syn. Agaricus blazei Murill) was discovered in the 1960s in the Piedade region of Brazil, where the local population had notably low rates of certain diseases. Brought to Japan for research, it quickly became one of the most studied medicinal mushrooms in the world. Its extraordinary beta-glucan content — up to 40% dry weight, the highest of any known mushroom — combined with its unique (1,3)/(1,6)-D-glucan structure makes it one of the most potent natural immune activators. Japanese clinical research has focused on its applications in oncology support, metabolic health, and allergy reduction.

Highest Beta-Glucan Content

Up to 40% beta-glucan content by dry weight — the highest of any known mushroom — providing exceptional immune activation per gram of extract.

Powerful NK Cell & Macrophage Activation

Unique (1,3)/(1,6)-D-glucan structure activates NK cells and macrophages through Dectin-1 and TLR-2 receptors, providing comprehensive innate immune activation.

Supports Healthy Blood Sugar Metabolism

Clinical studies in type 2 diabetes patients show significant improvements in insulin sensitivity and fasting blood glucose with Agaricus blazei supplementation.

Anti-Allergic & Anti-Inflammatory Effects

Modulates Th1/Th2 immune balance, reducing allergic responses and systemic inflammation.

Liver Protective Properties

Ergosterol and polysaccharides demonstrate hepatoprotective activity, supporting liver health and detoxification.

Applicazioni del prodotto

Premium Immune Activation FormulasMetabolic & Blood Sugar SupportOncology Support ProductsHigh-Potency Beta-Glucan SupplementsAllergy & Inflammation FormulasLiver Health Products