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All MushroomsShiitake
Lentinula edodes

Shiitake

The Heart-Healthy Mushroom

Beyond its global culinary fame, Shiitake contains lentinan — a clinically validated immune activator — and eritadenine, a unique compound that supports healthy cholesterol metabolism.

Family

Marasmiaceae

Origin

East Asia — China, Japan, Korea

Primary Benefit

Cardiovascular & Immune Health

Shiitake (Lentinula edodes) — raw medicinal mushroom

Circa Shiitake

Lentinula edodes is the world's second most cultivated mushroom and one of the most medicinally significant. Lentinan, its primary beta-glucan, was approved as an injectable immunotherapy in Japan for gastric cancer treatment in 1985. Eritadenine, a unique adenine derivative found only in Shiitake, has been shown to support healthy cholesterol metabolism by inhibiting the enzyme that converts homocysteine to methionine, thereby reducing plasma cholesterol levels. Shiitake is also an exceptional source of ergothioneine and B vitamins, making it a nutritionally dense ingredient for cardiovascular and immune health products.

Immune System Activation

Lentinan activates macrophages, NK cells, and cytotoxic T-lymphocytes, providing potent immune surveillance support.

Supports Healthy Cholesterol

Eritadenine has been shown to reduce total plasma cholesterol and LDL levels in multiple animal and human studies.

Cardiovascular Health

Eritadenine, ergothioneine, and beta-glucans collectively support vascular health, healthy blood pressure, and reduced oxidative stress in the cardiovascular system.

Rich in B Vitamins & Minerals

Provides a natural source of B vitamins, copper, selenium, zinc, and manganese — essential micronutrients for energy and immune function.

Antiviral Properties

Lentinan and other polysaccharides demonstrate antiviral activity against influenza and other viruses in laboratory studies.

Applicazioni del prodotto

Cardiovascular Health ProductsDaily Immune SupplementsFunctional Food IngredientsVitamin & Mineral ComplexesHeart Health FormulasCholesterol Support Products

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Dettagli di produzione

Metodo di estrazione

Hot water extraction to maximize lentinan and beta-glucan yield.

Standardizzazione

Standardized to ≥25% polysaccharides with verified lentinan content.

Formati disponibili

  • Powder (4:1, 8:1 extract)
  • Liquid Tincture (30ml, 50ml)
  • Capsule Fill
  • Functional Food Ingredient

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