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The Mushroom for the Mind
The only mushroom known to contain hericenones and erinacines — unique neuroactive compounds that stimulate Nerve Growth Factor (NGF) synthesis and cross the blood-brain barrier.
Family
Hericiaceae
Origin
North America, Europe, East Asia
Primary Benefit
Brain & Cognitive Health
Hericium erinaceus is the undisputed leader in the emerging category of nootropic mushrooms. Its two classes of unique bioactive compounds — hericenones (from the fruiting body) and erinacines (from the mycelium) — are the only naturally occurring small molecules known to stimulate the synthesis of Nerve Growth Factor (NGF) in the brain. NGF is essential for the growth, maintenance, and survival of neurons. This mechanism makes Lion's Mane uniquely positioned for products targeting cognitive performance, memory, neurological health, and mood. Clinical studies have demonstrated measurable improvements in mild cognitive impairment, anxiety, and depression.
Stimulates Nerve Growth Factor (NGF)
Hericenones and erinacines upregulate NGF synthesis, supporting neuronal growth, maintenance, and plasticity.
Enhances Memory & Focus
Clinical trials show significant improvements in cognitive function scores in adults with mild cognitive impairment after 16 weeks of supplementation.
Supports Nerve Regeneration
NGF stimulation promotes peripheral nerve repair, with potential applications in neuropathy and post-injury recovery.
Reduces Anxiety & Depression
A double-blind trial in menopausal women showed significant reductions in depression and anxiety scores after 4 weeks.
Gut-Brain Axis Support
Beta-glucans act as prebiotics, supporting the microbiome and the bidirectional gut-brain communication pathway.
Get a free Lion's Mane extract sample for your formulation trials. B2B clients only.
Extraction Method
Dual extraction (hot water + ethanol). Fruiting body preferred for hericenones; mycelium extract for erinacines.
Standardization
Standardized to ≥25% polysaccharides and verified hericenone content by HPLC.
Full B2B Inquiry
Custom volumes, pricing & formulation