GMP & ISO 22000 Certified Manufacturing — European Standards, Global Reach
B2B Inquiries · [email protected]
The Immune Warrior
Extensively studied in Japan and Korea for decades, Meshima's unique hispolon and polysaccharide compounds represent some of the most potent immune-modulating activity found in any medicinal mushroom.
Family
Hymenochaetaceae
Origin
Japan, Korea, China, Southeast Asia
Primary Benefit
Immune Defense & Anti-Tumor
Phellinus linteus, known as 'Meshima' in Japan (meaning 'women's island,' reflecting its traditional use in women's health), is one of the most pharmacologically active medicinal mushrooms. It has been the subject of extensive research in Japan, Korea, and China, with studies focusing on its immune-modulating, anti-tumor, and anti-inflammatory properties. Its unique bioactive compounds — particularly hispolon, interfungin A, and a range of polysaccharides and proteoglycans — demonstrate activity through multiple mechanisms, including direct immune cell activation and modulation of inflammatory cytokine cascades. Meshima is a premium, differentiated ingredient for advanced immune health formulations.
Potent Immune System Activation
Polysaccharides and proteoglycans activate macrophages, NK cells, and T-lymphocytes through multiple receptor pathways, providing comprehensive immune activation.
Studied for Anti-Tumor Properties
Hispolon and polysaccharides have demonstrated significant anti-tumor activity in preclinical models, with research ongoing into mechanisms of action.
Anti-Inflammatory Activity
Hispolon inhibits NF-κB signaling and reduces pro-inflammatory cytokine production, supporting a balanced inflammatory response.
Antioxidant Protection
Hispolon and inoscavins provide potent antioxidant activity, protecting cells from oxidative damage.
Supports Healthy Cell Cycle Regulation
Multiple compounds demonstrate activity in supporting healthy cell cycle checkpoints and apoptotic pathways in laboratory studies.
Get a free Meshima extract sample for your formulation trials. B2B clients only.
Extraction Method
Dual extraction (hot water + ethanol) to capture both polysaccharides and hispolon/phenolic compounds.
Standardization
Standardized to ≥20% polysaccharides with verified hispolon content by HPLC.
Full B2B Inquiry
Custom volumes, pricing & formulation