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The Pearl Oyster Mushroom
Oyster mushroom is one of the world's most cultivated and consumed medicinal fungi. Its naturally occurring lovastatin content, combined with pleuran beta-glucans and rich ergothioneine, makes it a powerful ally for cardiovascular health, cholesterol management, and immune support.
Family
Pleurotaceae
Origin
Worldwide — temperate and subtropical forests; widely cultivated globally
Primary Benefit
Cholesterol & Cardiovascular Health
Pleurotus ostreatus, the Pearl Oyster Mushroom, is one of the most widely cultivated mushrooms in the world, second only to the button mushroom. It grows naturally on dead and dying hardwood trees across temperate and subtropical regions. Its culinary popularity is matched by an impressive medicinal profile. Oyster mushroom contains naturally occurring lovastatin — the same class of compound as pharmaceutical statin drugs — which inhibits HMG-CoA reductase and supports healthy cholesterol metabolism. Its unique beta-glucan, pleuran, has demonstrated potent immune-modulating and anti-tumor activity in multiple studies. It is also rich in ergothioneine, the 'longevity vitamin' antioxidant, and contains mevinolin and other bioactive compounds.
Cholesterol Management
Naturally occurring lovastatin inhibits HMG-CoA reductase, supporting healthy LDL cholesterol levels. Multiple clinical studies confirm cholesterol-lowering effects.
Cardiovascular Health
Combined action of lovastatin, ergothioneine, and pleuran supports vascular health, reduces oxidative stress in the cardiovascular system, and promotes healthy endothelial function.
Immune Modulation
Pleuran activates macrophages, NK cells, and T-lymphocytes, supporting innate and adaptive immune defense.
Antioxidant & Anti-Aging
Ergothioneine and phenolic compounds provide robust antioxidant protection, particularly in high-oxidative-stress tissues.
Blood Pressure Support
GABA content and cardiovascular-protective compounds contribute to healthy blood pressure regulation.
Get a free Oyster extract sample for your formulation trials. B2B clients only.
Extraction Method
Hot water extraction to maximize pleuran, ergothioneine, and polysaccharide yield.
Standardization
Standardized to ≥20% polysaccharides with verified lovastatin and ergothioneine content by HPLC.
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