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All MushroomsEnoki
Flammulina filiformis

Enoki

The Golden Needle Mushroom

Enoki — the delicate golden needle mushroom — is one of the most consumed mushrooms in East Asia and a rising star in functional food science. Its unique protein Flammulin and beta-glucan content support immune defense and cognitive health.

Family

Physalacriaceae

Origin

East Asia — China, Japan, Korea; widely cultivated globally

Primary Benefit

Brain Health & Immunity

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About Enoki

Flammulina filiformis (formerly classified as F. velutipes) is the mushroom behind the iconic long, slender white cultivated enoki familiar in Asian cuisine. Wild enoki grows on dead elm, ash, and mulberry trees in autumn and winter, producing clusters of orange-brown caps. Cultivated enoki is grown in CO2-rich conditions producing the characteristic white, elongated form. Beyond its culinary popularity, enoki contains Flammulin — a unique ribosome-inactivating protein with demonstrated anti-tumor activity — as well as EA6, a polysaccharide that has shown remarkable results in clinical studies on allergic rhinitis and immune regulation. It is also one of the richest mushroom sources of ergothioneine.

Immune Modulation & Anti-Allergy

EA6 polysaccharide has demonstrated significant reduction in IgE-mediated allergic responses in clinical trials, including allergic rhinitis.

Cognitive & Brain Support

Ergothioneine accumulates in the brain and nervous system, providing neuroprotection against oxidative stress. Associated with reduced cognitive decline risk.

Anti-Tumor Properties

Flammulin and proflamin demonstrate anti-proliferative activity against multiple cancer cell lines in laboratory studies.

Gut Health & Prebiotic Activity

Beta-glucans and polysaccharides support beneficial gut microbiota and intestinal barrier integrity.

Antioxidant Protection

High ergothioneine and phenolic content provide robust antioxidant protection, particularly in high-oxidative-stress tissues.

Product Applications

Allergy & Respiratory FormulasBrain & Cognitive Health ProductsDaily Immune SupportAnti-Aging SupplementsFunctional Food IngredientsGut Health Blends

Request a Sample

Get a free Enoki extract sample for your formulation trials. B2B clients only.

Manufacturing Details

Extraction Method

Hot water extraction to maximize polysaccharide and Flammulin yield; standardized aqueous extract.

Standardization

Standardized to ≥20% polysaccharides with verified ergothioneine content by HPLC.

Available Formats

  • Powder (4:1, 8:1 extract)
  • Liquid Tincture (30ml, 50ml)
  • Capsule Fill
  • Allergy & Immune Blend Ingredient

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